Dermatopathology Primer of Cutaneous Tumors offers an in depth assessment of the most typical dermis neoplasms. for every neoplasm, the epidemiology, pathophysiology, scientific good points, medical variations, and targeted reviews are awarded in a succinct, bulleted shape. wide illustrations show every one neoplasm’s attribute gains, in addition to these of different tumors within the histological differential.
The booklet covers either benign and malignant cysts, epidermal, melanocytic, lymphoid, and delicate tissue neoplasms. It enhances the Dermatopathology Primer of Inflammatory ailments, written via authors of an identical team.
These books introduce the fundamental thoughts of dermatopathology to clinical scholars and citizens education in pathology and dermatology in addition to to different healthiness care pros looking a source for a uncomplicated realizing of dermatopathology.
Offered in an easy-to-read structure, the ebook presents a uncomplicated knowing of dermatopathology on which extra, deeper studying could be further, in addition to a brief visible connection with refresh the learner at the small print of every analysis. A reference part and word list are integrated for the good thing about non-dermatology experts.
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Extra resources for Dermatopathology Primer of Cutaneous Tumors
Histological features 1. Dermal cysts lined by two layers of epithelial cells 2. Outer layer of myoepithelial cells and inner layer of columnar with decapitation secretion Epidemiology • Occurs most commonly in middle-aged or elderly individuals Pathophysiology • It arises from the apocrine secretory coil Clinical features 1 2 Apocrine hidrocystoma Apocrine hidrocystoma Histological differential • Translucent, skin-colored to bluish cyst • 3–15 mm diameter • Typically found on face, neck, and periorbital region • Usually solitary lesion • Unusual in children Special studies • AH is S-100 negative, PAS positive; eccrine hidrocystomas are typically S-100 positive and PAS negative • AH expresses human milk-fat globulin antigen while eccrine hidrocystomas do not 1.
Cells with prominent oval nuclei and fine chromatin pattern 3. Lymphocytes and extravasated red cells are also seen Other features: • Typical mitoses are common • Some cells may have a ganglion like appearance • Capillaries with plump endothelial cells • Ossifying fasciitis shows areas with osteoid metaplasia Pathophysiology • Some patients with nodular fasciitis report trauma to the site of the lesion, but the majority do not • Birth trauma may be a factor in the genesis of cranial fasciitis 1,2 Clinical features 1,2 3 3 Nodular fasciitis Nodular fasciitis Histological differential 1.
Ducts lined by cuboidal epithelial cells and eosinophilic luminal cuticle 3. Frequent mitoses and sometimes necrosis 4. Squamous differentiation and clear cell changes 3 3 Porocarcinoma Histological differential 1. Squamous cell carcinoma: • No evidence of ductal differentiation • No poroid cells 2. indd 56 • Ducts lined by cuboidal cells and eosinophilic cuticle help to differentiate porocarcinoma from other malignant tumors 56 15/06/2015 16:06 TUMORS OF FIBROUS TISSUE Benign Tumors • Nodular fasciitis Introduction Epidemiology Nodular fasciitis is a benign reactive proliferation of fibroblast-like cells that appears as a well-circumscribed, subcutaneous, fascial or intramuscular nodule.
Dermatopathology Primer of Cutaneous Tumors