By Privatdozent Dr. Faruk Hadžiselimović (auth.)
Ferment, an indication of growth in any clinical box, has formerly been missing within the zone of cryptorchidism, the place the one task has been in bettering operative tools. Now, even if, profound alterations within the care of boys with cryptorchidism are being led to; rules are bobbing up from a clean examine comparative anatomy, and histological and experimental observa tions are being supplemented by means of scientific exams made attainable through new hormonal brokers. The therapy of cryptorchidism starts with its attractiveness by way of the pediatri cian, who formerly has proven little curiosity as a result of disappointing effects from chorionic gonadotropin management. As for the doctor, his bent towards recovery of standard anatomical relationships has saved his cognizance excited by the advance of higher surgical technics to convey the recalci trant testis into the scrotum. either experts have refrained from the primordial query of why the testis didn't descend thoroughly. If this have been recognized they might deal with the reason for cryptorchidism, and never be chuffed in simple terms with attempting to right its outcome. As one reads this publication, one sees that during so much sufferers cryptorchidism isn't really attributable to a few anatomical constitution blockading the best way or through a few deformity of the testis interfering with the shipping mechanism. fairly, deficiencies within the hormonal setting of the fetus retard the developmen tal sequences necessary to the conventional differentiation and descent of the testis. The medical answer is hence to supply the poor substances.
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Extra info for Cryptorchidism: Management and Implications
Liss, New York 42. Hadzise1imovic F (1981) Funktionelle Morphologie und Pathologie der Nebenhoden und ihr EinfluB auf den Descensus testiculorum. Morphol Med 1 : 31-42 43. Barrow M, Gough MH (1970) Bilateral absence of testes. Lancet 1 : 366 44. Dickinson SJ (1973) Structural abnormalities in the undescended testis. J Pediatr Surg 8: 523-527 45. Dean LA jr, Major WJ, Ottenheimer JE (1952) Failure offusion of the testis and epididymis. J Uro168: 754-758 46. Lythgoe PJ (1961) Failure of fusion of the testis and epididymis.
A total of 22 patients were examined. In none of the children in the prepubertal period was he able to establish any pathological changes at an ultrastructural level. From the age of 10 onwards in cryptorchid individuals, a progressive fibrosis of the peritubular connective tissue set in, accompanied by delayed maturation of the seminiferous tubule. This fibrosis, which became more marked in the third group (14- to 38-year-olds) is, in his opinion, of particular significance. The 721 biopsies examined in this study, taken from boys up to 16 years of age, only partly confirm Leeson's findings.
The differentiation of the epididymis parallels the degree of testicular descent. The epididymis always precedes the testis. x 5 be a motor nerve to the muscle . The intimate proximity of the cremaster muscle with the internal abdominal oblique muscle throughout the whole development indicates that the latter muscle may be the origin of the former (Figs. 4, 5, 6). The tunica spermatica extern a is generally accepted to be derived from the ex- As testicular descent is an event occurring in both rodents and humans, their similarities should help us to understand this mechanism.
Cryptorchidism: Management and Implications by Privatdozent Dr. Faruk Hadžiselimović (auth.)