Read e-book online Bacterial Invasion into Eukaryotic Cells: Subcellular PDF

By Tobias A. Oelschlaeger, Jörg H. Hacker

ISBN-10: 1441933301

ISBN-13: 9781441933300

ISBN-10: 147574580X

ISBN-13: 9781475745801

This most modern quantity within the first-class Subcellular Biochemistry sequence is the 1st try and supply an in-depth evaluation of the sector of bacterial mobilephone invasion. the present wisdom approximately all well-studied micro organism having the ability to invade eukaryotic cells is introduced jointly, together with micro organism pathogenic to people and animals in addition to the symbiotic rhizobia. numerous chapters additionally care for new methods and functions concerning invasive micro organism.
The booklet, inclusive of contributions from around the world specialists, discusses bacterial invasion skill in the context of bacteria-host mobile interplay with the focus on pathogenicity.

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Extra info for Bacterial Invasion into Eukaryotic Cells: Subcellular Biochemistry

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1997) reported that type 1 fimbriae mediate internalization of E. coli into macrophages in the absence of antibodies by an uptake pathway which advantageously leads to intracellular survival of E. coli, in contrast to normal phagocytosis of E. coli following opsonization. However, it is important to note that the ability to mediate invasion is not a general property of adhesins, and is found only in certain variants of adhesins. 2. Soluble Extracellular Matrix Proteins-a Linker Strategy for Bacterial Invasion Another bacterial strategy utilized to induce internalization is to bridge a surface-attached bacterial ligand with a host soluble protein which can then bind to an eukaryotic internalization receptor.

65:2950-2958. , 1994, Some structures and processes of human epithelial cells involved in uptake of enterohemorrhagic Escherichia coli 0157:H7 strains, Infect. lmmun. 62:5142-5150. Oelschlaeger, T. , 1993, Unusual microtubule-dependent endocytosis mechanisms triggered by Campylobacter jejuni and Citrobacter freundii, Proc. Nat/. Acad. Sci. USA 90:6884-6888. , 1997, Characterization of the Chlamydia trachomatis vacuole and its interaction with the host endocytic pathway in HeLa cells, Infect. lmmun.

1999). For any of the above-mentioned receptors, it is not understood whether the receptor is specifically associated with the microtubular skeleton and, if so, whether the connection is direct or indirect. Nevertheless, there are host membrane proteins with documented connections to microtubules. Transferrin uptake via the transferrin receptor in hemopoetic, but not adherent, cell lines is inhibitable by MT depolymerization (Subtil and Dautry-Varsat, 1997). Furthermore, the glycine receptor as well as the yaminobutyric acid receptor in neuronal cells seem to be connected to MTs.

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Bacterial Invasion into Eukaryotic Cells: Subcellular Biochemistry by Tobias A. Oelschlaeger, Jörg H. Hacker

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