By J.-P. Montani, B. N. Van Vliet (auth.), Professor Thomas Unger, Professor Bernward A. Schölkens (eds.)
Nearly thirty years in the past, in 1974, the amount on Angiotensin edited through Irvine H.Page and F. Merlin Bumpus elevated the guide of Experimental Pharmacology. Even after 20 years the multiplicity of its activities appears to be like to not were totally chanced on. to name awareness to its many features is likely one of the reasons of this e-book. This new version of the amount on Angiotensin makes an attempt to supply an up to date account of the information and findings amassed because the complexity of angiotensin used to be so adequately recognized.
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61 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . or granulated cells in the kidney evolved at an early stage of vertebrate phylogeny. Angiotensin (Ang) I and II molecules have been biochemically identified in representative species of all vertebrate classes, and Ang II structure is well preserved throughout the phylogenetical scale. Ang receptors have also been identified pharmacologically and, in limited species, molecularly characterized.
2003). Unidentified Angiotensin Receptors and Signaling. Pharmacological and molecular studies suggest the presence of another unidentified receptor(s) in vertebrates (Smith 1996) (Table 3). The dogfish, an elasmobranch, has a CGP-sensitive receptor in the rectal gland and an interrenal receptor that has considerable 42 H. 15 30 81 Signaling losartan PO 2-5 -10 -50 41000 55000 49000 Reference CGP -100 1710 Functionl Action [Ca2+]ii la-hydroxycorticosterone secretion? TIerney et al. 1997 Armour et al.
Or granulated cells in the kidney evolved at an early stage of vertebrate phylogeny. Angiotensin (Ang) I and II molecules have been biochemically identified in representative species of all vertebrate classes, and Ang II structure is well preserved throughout the phylogenetical scale. Ang receptors have also been identified pharmacologically and, in limited species, molecularly characterized. The renin-angiotensin system (RAS) is important in maintaining blood pressure! blood volume homeostasis and ion-fluid balance.
Angiotensin Vol. I by J.-P. Montani, B. N. Van Vliet (auth.), Professor Thomas Unger, Professor Bernward A. Schölkens (eds.)