By Edited by Andrew D. Blann Edited by Gregory Y. H. Lip
ISBN-10: 0727917714
ISBN-13: 9780727917713
Urban clinic, Birmingham, united kingdom. Discusses the explanations and outcomes of blood clots, how antithrombotic treatment works and its makes use of for sufferers. Addresses bleeding hazards, venous thromboembolism, atrial traumatic inflammation, peripheral vascular affliction, middle failure, and anticoagulation. plentiful halftone and colour illustrations. Softcover.
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Extra info for ABC of Antithrombotic Therapy
Sample text
Thus, aspirin can be started in patients with suspected ischaemic stroke even when computed tomography is not available immediately. Anticoagulation treatment Heparin is not routinely recommended for patients with acute ischaemic stroke. There are no randomised trials supporting the use of standard doses of heparin (for example > 10 000 IU daily) even in patients with acute stroke and risk factors for recurrent events. The risk:benefit ratio of heparin administration is narrow, ill defined, and probably depends on the pathophysiological subtype of stroke and the factors that predispose to haemorrhage.
This effect is generally not accepted to be an improvement in the diseased segment of blood vessel, but the formation of collateral vessels perfusing the ischaemic tissue. Vasodilating agents, such as naftidrofuryl, have little value in managing claudication and peripheral vascular disease as their effect is small and does not stop progression of the disease. Cilostazol has been shown to increase absolute walking distance in some patients by up to 47%. However, it has no clear antithrombotic effect and has not been shown to stop disease progression.
BMJ 1994;308:81-106 + Antiplatelet Trialists’ Collaboration. Collaborative overview of randomised trials of antiplatelet therapy II: maintenance of vascular graft or arterial patency by antiplatelet therapy. BMJ 1994;308:159-68 + Antithrombotic Trialists’ Collaboration. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction and stroke in high risk patients. BMJ 2002;324:71-86 The survival curve from the CAPRIE study is adapted from CAPRIE Steering Committee, Lancet 1996;348:1329-39.
ABC of Antithrombotic Therapy by Edited by Andrew D. Blann Edited by Gregory Y. H. Lip
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